Phenylmagnesium Bromide With 2 Butanone Reaction

200983the multistep synthesis of 4hydroxy4,4diphenyl2butanone from ethyl acetoacetate illustrates the use of a ketal protecting group reaction of ethyl acetoacetate with ethylene glycol with ptsoh in toluene produced the ketal estereaction of the crude ketal ester with two equivalents of phenyl magnesium bromide followed by an aqueous acid workup generated the tertiary alcohol and.

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